Eoin Brodie is a Staff Scientist in the Ecology Department of the Earth Sciences Division of Lawrence Berkeley National Lab and an Adjunct Assistant Professor at the University of California, Berkeley in the Department of Environmental Science, Policy and Management. He obtained his Ph.D. from University College Dublin in Ireland and joined LBNL following postdoctoral research at UC Berkeley.
He serves on the Editorial Board of Microbiome, on the Academic Editorial Board of Peer J and is an Associate Editor for Frontiers in Terrestrial Microbiology. For his role in development of the Berkeley Lab PhyloChip with Gary Andersen, Todd DeSantis and Yvette Piceno, in 2008 he was awarded an R&D100 award in addition to a Wall St Journal Technology Innovation award. He is a member of the American Society for Microbiology, American Geophysical Union, International Society for Microbial Ecology and the International Society for Subsurface Microbiology.
His research focuses on the feedbacks between microbial communities and their environment with a goal towards developing a predictive understanding of how biogeochemical cycles are regulated and how human health is impacted. The general approach can be considered ‘reverse engineering’, that is deconstructing naturally occurring microbial communities with desired properties to identify the functional roles of specific microorganisms, key inter-species interactions and critical environmental or host factors that influence the assembly and maintenance of these populations.
This reverse engineering requires a range of technical approaches across scales. Dr. Brodie’s group combines cutting edge molecular biology tools (next generation DNA/RNA sequencing), custom high-density microarrays, stable isotope tracers, microelectrodes, high throughput (HTP) cultivation, HTP biochemical assays and HTP functional metagenomic screening using robotics. Through collaborations we also carry out NanoSIMS spectroscopy to identify substrate incorporation in microbial communities (with Jennifer Pett-Ridge and the NanoSIMS group @ LLNL); Synchrotron Fourier Transform InfraRed (S-FTIR) spectroscopy (with Hoi-Ying Holman and the Chemical Ecology group @ LBNL) to non-destructively monitor changes in microbial physiology or substrate transformation; and environmental metabolomics of soil microbial communities (with Trent Northen and his group @ LBNL).
The activity of microorganisms in soil and subsurface systems is a particular research focus with several ongoing projects related to predicting climate change impacts on soil biogeochemical cycles. More recently the Brodie group has begun research into microbe host interactions in insect systems with relevance to biofuel production and agricultural productivity. The group also develops cutting-edge technology to monitor microorganisms (including pathogenic species of clinical relevance) and their activities in the environment.
The Brodie Group is primarily funded by the following agencies.
Eoin L. Brodie
Lawrence Berkeley National Lab
1 Cyclotron Rd, MS-70A3317
Berkeley, CA, 94720